With a weak lesion of the larvae of the large gastric, easternand hemorrhoidal gadflies are localized in the cardial parts of the stomach and do not cause noticeable disorders from the body.
With severe damage (more than 200 larvae), they are localized not only in the cardiac, but also in the pyloric part of the stomach, as well as on the mucous membrane of the duodenum. In such cases, gadfly larvae affect not only the mucous membranes, but also the secretory glands and nerve endings of the symptomatic and vagus nerves, which leads to a violation of the secretory and motor function of the entire gastrointestinal tract, involving the entire host organism in the disease process.
Prolonged disruption of the normal functioning of the digestive tract leads to insufficient absorption of food, a decrease in fatness. In many horses, as a result of parasitism of gastrofilus, degeneration occurs, and in some animals, perforation of the duodenum or stomach.
Horses infested with larvae are in a state of sensitization with larval metabolic products. Parenteral administration of an aqueous extract obtained from the bodies of the larvae causes symptoms of turbulently leaking pegs with symptoms of impaired activity of the cardiovascular system.
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